| Metastatic or otherwise incurable malignancy |
| Hospital length of stay of 10 days prior to transfer to the ICU |
| Duration of ongoing invasive mechanical ventilation of 7 days or more |
| ICU length of stay of 14 days or more |
| Age 80 years old or older with 2 or more significant chronic diseases, (e.g. chronic obstructive pulmonary disease requiring home oxygen therapy, chronic kidney disease requiring renal replacement therapy); |
| Out of hospital or in-hospital cardiac arrest |
| Cerebral hemorrhage requiring mechanical ventilation |
| Admission to the ICU from a long-term acute care hospital |
