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. 2015 Sep 15;100(2):261–274. doi: 10.1189/jlb.3HI0515-200RR

Figure 6. Inhibition of Notch signaling suppresses inflammatory responses in placental cells.

Figure 6.

Proinflammatory cytokines and chemokines were measured by Luminex assay in protein extracted from placental cells recovered from mouse on d 14.5 of pregnancy, cultured ex vivo, and treated with PBS and LPS for 2 h, followed by treatment with control or GSI (an inhibitor of Notch receptor processing) for 10 h; n = 3/group. Error bars ± sem. *P ≤ 0.05; **P ≤ 0.01, significant difference between LPS treated with control/GSI.