TABLE 1.

Effect of IR on cytokine secretion by mDCs

Cytokine	% Remaining secretion	sd	P
IL-23	43	11	<0.0001
IL-12	89	16.3	0.0005
IL-27	100.9	36.6	ns
IL-1β	93.5	34.4	ns
TNF-α	111.8	29.6	ns
IL-6	174.1	114.4	ns
IL-10	95.9	6.2	ns

DCs were irradiated (6 Gy) or nonirradiated before activation with LPS/IFN-γ. Supernatants were collected following 24 h incubation, and secreted IL-23, IL-12, IL-27, IL-1β, TNF-α, IL-6, and IL-10 were measured by ELISA. All experiments were repeated at least 4 times in triplicate, and significance was assessed with 2-way ANOVA.