Table 1.

Inhibition of nAChR subtypes by membrane cholesterol

Time (min)	Decrease in macroscopic current [% ± SEM (n)]
	Torpedo	Muscle	α7	α4β2
15	28 ± 4 (19)	8 ± 5 (8)	35 ± 5 (21)	16 ± 3 (25)
30	26 ± 4 (14)	29 ± 7 (8)	35 ± 6 (15)	22 ± 5 (13)
45	38 ± 9 (10)	46 ± 5 (8)	52 ± 8 (11)	34 ± 6 (10)

Two-tailed, unpaired t test analysis. Statistically significant differences: Torpedo versus Muscle (15 min) P = 0.0095, Torpedo versus α4β2 (15 min) P = 0.0126, Muscle versus α7 (15 min) P = 0.0035, α7 versus α4β2 (15 min) P = 0.0006