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. Author manuscript; available in PMC: 2017 Jul 14.
Published in final edited form as: J Med Chem. 2016 Jun 24;59(13):6512–6530. doi: 10.1021/acs.jmedchem.6b00719

Figure 13.

Figure 13

Measurement of the association constant between compound 15a and Fe(III)PPIX at pH 7.5 in 40% v/v DMSO. Plots of a) the hypochromic effect on the Fe(III)PPIX absorbance spectrum with increasing compound concentration, exhibiting isosbestic points (*) and b) the maximum Fe(III)PPIX absorbance vs the concentration of compound 15a fitted to a 1:1 association isotherm.