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. Author manuscript; available in PMC: 2017 Jul 14.
Published in final edited form as: J Med Chem. 2016 Jun 24;59(13):6512–6530. doi: 10.1021/acs.jmedchem.6b00719

Figure 6.

Figure 6

(a) βH inhibitory SARs for the dibenzamides and (b) a possible mode of interaction to explain the observed βH inhibition activities. In this example, the dibenzamide, 15h interacts with the fastest growing Hz crystal face7 with the R1 t-butyl moiety directed outwards. Graphics were supplied by R. Muller and generated using Materials Studio.55