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. Author manuscript; available in PMC: 2017 Jul 14.
Published in final edited form as: J Med Chem. 2016 Jun 24;59(13):6512–6530. doi: 10.1021/acs.jmedchem.6b00719

Figure 9.

Figure 9

Dose response curves for the non-Hz heme and the % parasite survival, which cross near the parasite survival IC50 for compounds a) 12d and b) 15i. Scales adjusted so that the IC50 for parasite survival coincides with 50% of the final value for increase in free heme (indicated by the dotted line).