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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Hypertension. 2016 Jun 13;68(2):411–417. doi: 10.1161/HYPERTENSIONAHA.116.07515

Figure 1.

Figure 1

CAs were induced in 56 C57BL/6J mice divided equally into mice receiving vehicle only (DMSO), aspirin (25 mg/kg/day IP), Cox-1 inhibitor (Sc-560 10mg/kg/day IP), and Cox-2 inhibitor (NS-398 20 mg/kg/day IP). (1A, upper left graph) Aspirin and Cox-2 inhibitor did not alter the rate of CA formation in mice. (1B, upper right graph) Aspirin and Cox-2 inhibitor significantly reduced the risk of SAH in mice. (1C, lower graph) Aspirin and Cox-2 inhibitor significantly prolonged asymptomatic survival in mice.

* indicates statistically significant difference.