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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Hypertension. 2016 Jun 13;68(2):356–364. doi: 10.1161/HYPERTENSIONAHA.116.07564

Table 3.

Race/ethnic-specific association results for SNPs identified in association with blood pressure traits in MESA.

Trait SNP (Effect
/ other
allele)		 Group Effect
allele
frequency		 N Beta SE P-value
SBP rs1731243*
(C/T)		 White 0.38 2453 1.09 0.57 0.058
African American 0.76 2553 2.09 0.76 0.006
Hispanic 0.35 2106 1.20 0.71 0.093
Chinese 0.75 706 1.44 1.34 0.283
Meta-analysis 1.38 0.37 1.9E-04
MAP rs13394970*
(T/G)		 White 0.38 2460 0.77 0.35 0.029
African American 0.45 2550 0.79 0.40 0.049
Hispanic 0.30 2107 0.97 0.45 0.031
Chinese 0.75 706 0.75 0.82 0.361
Meta-analysis 0.82 0.22 1.9E-04
HTN rs1731243*
(C/T)		 White 0.38 2464 0.12 0.07 0.070
African American 0.76 2556 0.17 0.08 0.032
Hispanic 0.35 2113 0.20 0.08 0.008
Chinese 0.75 707 0.24 0.15 0.106
Meta-analysis 0.17 0.04 4.6E-05

Genetic association results for medication-corrected blood pressure traits reported under an additive 1 d.f. SNP dosage model. Analysis of blood pressure traits and prevalent hypertension conducted with adjustment for sex, age, age2, body mass index, study site and race/ethnic specific PCs of ancestry.

*

Most strongly associated SNP in meta-analysis for the indicated gene and trait.