Figure 2.

Aggregating studies of psychophysiological interactions. Aggregating across PPI studies requires explicit consideration of the variables that contribute to the psychophysiological interactions: the seed region and the psychological context. (A) We identified common seed regions within our corpus of PPI studies using a coordinate‐based meta‐analytic approach. This analysis revealed several regions that were commonly used as seed regions: the amygdala, ventral paracingulate cortex (vPAC), superior temporal gyrus (STG), and dorsolateral prefrontal cortex (DLPFC), fusiform face area (FFA), ventral striatum, anterior insula (aINS), dorsal paracingulate cortex (dPAC), and superior parietal lobe (SPL). (B) We then parsed studies according to the general psychological context used in the PPI analysis (see Materials and Methods for article coding scheme). The matrix depicts the number of studies using a particular combination of seed region and psychological context (i.e., a specific PPI). Our primary analyses focused on bidirectional contrasts of cells containing 10 or more studies (gray), excluding those in the miscellaneous category. [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]