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Survivin wt, 2b and Δex3 isoforms are highly correlated and show higher expression in high-grade chondrosarcoma as determined by Q-PCR analysis. (a–c) Survivin isoforms wt (a), 2b (b) and Δex3 (c) are highly expressed in high-grade (grade II and III) chondrosarcoma compared with low-grade (ACT) chondrosarcoma. No expression is found in cartilage while variable expression is seen in growth plate tissue. Each dot represents one measurement, and mean values are shown for each group.
