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. Author manuscript; available in PMC: 2016 Jul 15.
Published in final edited form as: J Bone Miner Res. 2014;29(5):1183–1195. doi: 10.1002/jbmr.2150

Fig. 3.

Fig. 3

Combined treatment with PA and OA inhibits PA-enhanced osteoclastogenesis. (A) TRAP staining in osteoclasts (5 days post-stimulation with RANKL) treated with PA, OA, or PA and OA. (B) Average size of osteoclasts treated with PA, OA, or PA and OA. Average size was calculated from measurement of 173 osteoclasts in control treatment, 108 osteoclasts in PA-treated cultures, 109 osteoclasts in OA-treated cultures, and 133 osteoclasts in cultures treated with combination of PA and OA; *p < 0.05. (C) RT-PCR analysis for TRAP, PGC1β, TNFα, and RANK mRNAs; *p < 0.05, ***p < 0.001, n = 4 to 9.