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. 2016 Jun 21;173(15):2369–2389. doi: 10.1111/bph.13514

Figure 6.

Figure 6

Dietary capsaicin increases the expression of pgc‐1α, sirt‐1 and prdm‐16 in EF and SCF of WT but not TRPV1−/− mice. The average mRNA levels ± SEM of pgc‐1α, sirt‐1 and prdm‐16 normalized to NCD in EF (A, C and E) and SCF (B, D and F) are given for NCD‐fed, HFD‐fed or HFD + CAP‐fed WT and TRPV1−/− mice (n = 40). (G) Representative Western blot for PRDM‐16 expression in SCF of WT and TRPV1−/− mice. (H) Ratio of mean band intensity ± SEM between PRDM‐16 and β‐actin. $$ and ** P < 0.05; significantly different as indicated.