Table 4.
Fetal weights obtained at the time of cesarean section and offspring body weight at PND 14
| Con+Reg | Con+HFD | IUGR+Reg | IUGR+HFD | |
|---|---|---|---|---|
| Fetal rat | ||||
| Male | ||||
| Body weight (g) | 4.3 ± 0.2 | 3.9 ± 0.6a | 3.3 ± 0.4a | 3.2 ± 0.3a , b |
| Brain weight (g) | 0.17 ± 0.01 | 0.18 ± 0.01 | 0.16 ± 0.01 | 0.16 ± 0 |
| Brain:body weight ratio | 0.04 ± 0 | 0.05 ± 0a | 0.06 ± 0a | 0.06 ± 0.1a , b |
| Liver weight (g) | 0.32 ± 0 | 0.29 ± 0.01 | 0.16 ± 0.02a | 0.2 ± 0.03a , b |
| Liver:body weight ratio | 0.07 ± 0 | 0.07 ± 0 | 0.05 ± 0a | 0.06 ± 0.01a |
| Placenta weight (g) | 0.73 ± 0.05 | 0.63 ± 0.02 | 0.54 ± 0.04a | 0.66 ± 0.05 |
| Placental efficiency (g/g) | 6.2 ± 0.4 | 6.2 ± 0.4 | 5.8 ± 0.5 | 4.9 ± 0.3a , b |
| Female | ||||
| Body weight (g) | 4.2 ± 0 | 3.6 ± 0.5a | 3 ± 0.6 | 2.9 ± 0.2a , b |
| Brain weight (g) | 0.17 ± 0 | 0.16 ± 0.01 | 0.17 ± 0 | 0.15 ± 0.01 |
| Brain:body weight ratio | 0.04 ± 0 | 0.05 ± 0 | 0.06 ± 0a | 0.05 ± 0a , b |
| Liver weight (g) | 0.31 ± 0.01 | 0.26 ± 0.02a | 0.21 ± 0.02a | 0.19 ± 0.03a , b |
| Liver:body weight ratio | 0.08 ± 0 | 0.07 ± 0 | 0.06 ± 0 | 0.07 ± 0 |
| Placenta weight (g) | 0.76 ± 0.07 | 0.67 ± 0.03 | 0.55 ± 0.04a | 0.68 ± 0.04 |
| Placental efficiency (g/g) | 5.8 ± 0.5 | 5.5 ± 0.3 | 5.8 ± 0.7 | 4.3 ± 0.3a , b |
| PND 14 rat | ||||
| Male | ||||
| Body weight (g) | 36.7 ± 0.9 | 35.7 ± 0.6 | 34.2 ± 1.5a | 33.3 ± 0.5a , b |
| Female | ||||
| Body weight (g) | 36.3 ± 1.1 | 34 ± 0.6a | 32.1 ± 1.1a | 31.2 ± 1a , b |
Offspring from n = 10 rat dams per group. Offspring body and organ weights were obtained from two male and two female offspring from each dam, averaged per sex, and the litter average per sex averaged over the 10 dams. Data are shown as mean ± SEM. HDL, high‐density lipoprotein, HFD, high‐saturated‐fat diet; IUGR, intrauterine growth restriction.
a
P ≤ 0.05 compared to Con+Reg.
b
P ≤ 0.05 compared to Con+HFD.