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. 2015 Dec 23;1(4):e00049. doi: 10.1016/j.heliyon.2015.e00049

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© 2015 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Average DNA oxidation (during 15 minutes) dependence upon H₂O₂ external concentration and maximal Fe²⁺ recycling rate v_max. C₀ is set to 1 mM. Initially, cell density was set to 10⁷ cell/mL. The kinetic parameters used for the simulation are gathered in Table 1.