Table 4. Genotype and allelic distribution of rs l7222919 and rs9579646 in IS and control subjects.
| Genotype | IS subjects (n,%) | Control subjects (n,%) | P value | OR(95% CI) |
|---|---|---|---|---|
| rs l7222919 | ||||
| TT | 525 (64.8) | 486 (58.9) | 1.000 | |
| TG | 258 (31.9) | 296 (35.9) | 0.043 | 0.807 (0.656~0.993) |
| GG | 27 (3.3) | 43 (5.2) | 0.031 | 0.581 (0.354~0.955) |
| allele | ||||
| T | 1308 (80.7) | 1268 (76.8) | 1.000 | |
| G | 312 (19.3) | 382 (23.2) | 0.007* | 0.792 (0.669~0.937) |
| rs 9579646 | ||||
| AA | 185 (22.8) | 179 (21.7) | 1.000 | |
| AG | 391 (48.3) | 422 (51.2) | 0.386 | 0.896 (0.700~1.148) |
| GG | 234 (28.9) | 224 (27.1) | 0.939 | 1.011 (0.768~1.331) |
| A | 761 (47.0) | 780 (47.3) | 1.000 | |
| G | 859 (53.0) | 870 (52.7) | 0.865 | 1.012 (0.882~1.161) |
The P value and OR (95% CI) were adjusted for confounding factors such as age, gender, hypertension, diabetes, smoking, drinking, TC and TG. *express the adjusted P value for significance P < 0.025.