Table 1. Previous studies reporting abnormalities of functional brain networks in AD.

Study	Brain signal	Connectivity measure	Binarization	Findings
Seo, et al.57	PET	Correlation	Density	Decreased CC and no change in APL
van Haan et al.63	MEG	Synch Likelihood	NA	Decreased modularity in lower bands and increased modularity in higher bands
Stam et al.4	EEG	Synch Likelihood	Threshold/Density	Increased APL and no change in CC
De Haan & Jalili58	EEG	Synch Likelihood	Density	Decreased CC in alpha and beta bands and decreased APL in alpha and gamma bands
Afshari et al.22	EEG	Coherence	Density	Decreased GE and increased LE in alpha and beta bands
Spekar et al.59	fMRI	Correlation	Threshold	Decreased CC
Zhao et al.52	fMRI	Correlation	Density	Increased LE and decreased GE
Ciftci64	fMRI	Coherence	MST	No change in the degree distribution
Sanz-Arigita et al.62	fMRI	Synch Likelihood	Threshold/Density	Decreased APL and no change in CC
Stam et al.20	MEG	Phase Synch	NA	Decreased CC and APL in alpha band
Brier et al.60	fMRI	Correlation	Density	No change in APL and reduced CC and modularity
Li et al.61	fMRI	Correlation	Threshold	Decreased GE and CC
Wang et al.23	fMRI	Correlation	Threshold	Increased APL

APL: Average Path Length, CC: Clustering Coefficient, GE: Global Efficiency, LE: Local Efficiency.