Table 1.
Clinical characteristics of the study subjects
| Hepatitis B-associated HCC (n = 30) | Hepatitis C-associated HCC (n = 38) | P value | |
| Sex (M/F) | 28/2 | 22/16 | < 0.011 |
| Age (yr) | 62.6 ± 10.9 | 73.4 ± 9.7 | < 0.012 |
| Albumin (g/dL) | 3.4 ± 0.6 | 3.4 ± 0.5 | NS2 |
| Total bilirubin (mg/dL) | 1.2 ± 0.6 | 1.4 ± 1.3 | NS2 |
| AST (U/L) | 75.6 ± 76.2 | 57.8 ± 31.6 | NS2 |
| ALT (U/L) | 54.3 ± 38.4 | 49.8 ± 38.3 | NS2 |
| Fasting blood glucose (mg/dL) | 104.5 ± 22.2 | 113.1 ± 36.0 | NS2 |
| γ-glutamyl transferase (U/L) | 77.0 ± 64.8 | 60.4 ± 58.1 | NS2 |
| Creatinine (mg/dL) | 0.73 ± 0.19 | 1.01 ± 1.53 | NS2 |
| Platelet count (× 103/μL) | 13.5 ± 8.4 | 11.7 ± 4.7 | NS2 |
| Fib-4 index | 5.7 ± 4.4 | 6.4 ± 3.9 | NS2 |
| AFP (ng/mL) ≤ 6.2 /> 6.2 | 10/20 | 8/30 | NS1 |
| DCP (mAU/mL) ≤ 40 /> 40 | 17/13 | 24/14 | NS1 |
| HBs antigen, positive | 30 | 0 | |
| HCV-antibody, positive | 0 | 38 | |
| HBV genotype (A/B/C/D) | 0/14/15/1 | NA | |
| HCV genotype (1b/2a/2b) | NA | 34/4/0 |
1
Fisher exact test;
2
Mann-Whitney U-test. Data were expressed as mean ± SD. AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; NS: Not significant; NA: Not applicable; DCP: Des-γ-carboxy prothrombin; HCC: Hepatocellular carcinoma.