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. 2016 Feb 10;2(4):241–250. doi: 10.1021/acsinfecdis.5b00117

Figure 5.

Figure 5

(A) Zeta potential of AuNC@PDA (squares) and loading capacity of Dap (triangles) as a function of pH value. (B) Release profiles of Dap upon irradiation by a diode laser at 808 nm with a power density of 1.67 W/cm2 at a concentration of 0.4 nM AuNCs with different Dap loadings: 4 μg/mL or 6.2 × 103 Dap molecules per AuNC (AuNC@DapLo/PDA, squares) and 16 μg/mL or 2.5 × 104 Dap per AuNC (AuNC@DapHi/PDA, diamonds). (C) Bacterial killing without irradiation and treatment of (1) 2 μg/mL Dap, (2) 5 μg/mL Dap, (3) AuNC@DapLo/PDA (4 μg/mL), and (4) AuNC@DapHi/PDA (16 μg/mL) and with irradiation (5) 2 μg/mL Dap and (6) AuNC@DapLo/PDA (4 μg/mL, 2 μg/mL released). Killing was assessed at 0 h (striped bars) and 24 h (solid bars) post treatment. Black bars indicate non-irradiated groups, and red bars indicate irradiated groups.