Table 4.
Prevalence of Previously Reported Potential Risk Factors for Methicillin-Resistant Staphylococcus aureus Community-Acquired Pneumonia, by Etiology Group
| Characteristic | MRSA CAP, n (%) (n = 15) | Methicillin-Susceptible Staphylococcus aureus CAP, n (%) (n = 22) | Pneumococcal CAP, n (%) (n = 115) | P Valuea (MRSA vs Pneumococcal) | All-Cause non- Staphylococcus aureus CAP, n (%) (n = 2222) | P Valuea (MRSA vs All-Cause non- Staphylococcus aureus) |
|---|---|---|---|---|---|---|
| Hemodialysis use | 3 (20.0) | 2 (9.1) | 3 (2.6) | 0.02 | 82 (3.7) | 0.02 |
| Seizure disorder | 1 (6.7) | 1 (4.6) | 4 (3.5) | 0.46 | 85 (3.8) | 0.45 |
| Diabetes mellitus | 7 (46.7) | 8 (36.4) | 23 (20.0) | 0.04 | 569 (25.6) | 0.08 |
| Recurrent soft tissue infections | 1 (6.7) | 4 (18.2) | 9 (7.8) | 1.00 | 145 (6.5) | 1.00 |
| Hemoptysis | 2 (13.3) | 3 (13.6) | 13 (11.3) | 0.68 | 192 (8.6) | 0.38 |
| Daily alcohol use | 1 (6.7) | 3 (13.6) | 11 (9.6) | 1.00 | 156 (7.0) | 1.00 |
| Multilobar or cavitary infiltrates | 5 (33.3) | 7 (31.8) | 39 (33.9) | 1.00 | 667 (30.0) | 0.78 |
| Pleural effusion | 4 (26.7) | 5 (22.7) | 41 (35.7) | 0.58 | 687 (30.9) | 1.00 |
| Concurrent influenza infection | 1 (6.7) | 2 (9.1) | 4 (3.5) | 0.46 | 129 (5.8) | 0.59 |
| Current proton pump inhibitor use prior to admission | 5 (33.3) | 5 (22.7) | 18 (15.6) | 0.14 | 505 (22.7) | 0.35 |
| Outpatient antibiotic use prior to admission | 2 (13.3) | 0 | 15 (13.0) | 1.00 | 440 (19.8) | 0.75 |
Abbreviations: CAP, community-acquired pneumonia; MRSA, methicillin-resistant Staphylococcus aureus.
a P values calculated using Fisher exact test.