Figure 2.

Parvalbumin (PV) density is unchanged, but PV levels are lower in schizophrenia subjects. (a–d) Unity plots in which each data point represents a subject pair and data points below the unity line indicate lower values in the schizophrenia subject relative to the matched comparison subject. (a) The density of PV cells seen under low magnification is lower in schizophrenia subjects. (b) The density of PV cells seen under high magnification is not affected by disease status. Soma PV labeling in PV cells in schizophrenia subjects is lower in (c) PV cells with an aggrecan perineuronal nets (PNNs) and (d) PV cells lacking a PNN.