Table 2. DDC Activity (K i) by Haplotype 4 Status.
|
DDC activity (Ki) |
||||
|---|---|---|---|---|
| Region | Haplotype 4 status | Mean | SEM | SD |
| Ventral striatum | Noncarrier | 9.15 × 10−3 | 1.09 × 10−4 | 1.12 × 10−3 |
| Carrier | 9.85 × 10−3 | 2.63 × 10−4 | 1.02 × 10−3 | |
| Caudate | Noncarrier | 9.78 × 10−3 | 9.12 × 10−5 | 9.34 × 10−4 |
| Carrier | 9.76 × 10−3 | 2.64 × 10−4 | 1.02 × 10−3 | |
| Putamen | Noncarrier | 1.10 × 10−2 | 9.85 × 10−5 | 1.01 × 10−3 |
| Carrier | 1.15 × 10−2 | 2.43 × 10−4 | 9.41 × 10−4 | |
| Ventral striatum peak | Noncarrier | 3.00 × 10−3 | 4.56 × 10−5 | 4.67 × 10−4 |
| Carrier | 3.42 × 10−3 | 1.18 × 10−4 | 4.57 × 10−4 | |
| Putamen peak | Noncarrier | 7.61 × 10−3 | 8.79 × 10−5 | 9.01 × 10−4 |
| Carrier | 8.38 × 10−3 | 2.89 × 10−4 | 1.12 × 10−3 | |
Mean, standard error (SEM), and SD values for Ki measured for each ROI and peak ventral striatum and putamen foci (see Figure 1) from the voxel-wise analyses. Peak foci values for each subject were defined as the mean Ki within a sphere, centered at the peak voxel coordinates and of radius 4.5 mm.