Table 3. Brain Regions Showing a Significanta Correlation between fALFF and Symptom Severity within the Clinical High Risk for Psychosis (CHR) Group.

SOPS symptom rating	Cluster anatomy	FWE cluster-corrected p-value	Cluster size (in 3 mm3 voxels)	Peak MNI coordinate (x, y, z)
Negative correlation: higher LFO activity associated with lower symptom severity
Unusual thought content/delusional ideas	Bilateral superior parietal lobule/precuneus BA: 7, 31	p=0.01	153	6, −55, 37
Unusual thought content/delusional ideas	Left temporoparietal junction, extending to occipital cortex BA: 7, 19, 39	p=0.001	234	−39, −76, 31
Positive correlation: higher LFO activity associated with greater symptom severity
Negative symptom average	Left inferior prefrontal cortex BA: 47	p=0.007	170	−39, 44, 19
Disorganized symptom average	Left inferior frontal and anterior insular cortex BA: 13, 46, 47	p=0.002	212	−36, 32, 22

Abbreviation: BA, Brodmann area.

^aCluster-corrected p-values are familywise error (FWE) corrected and based on a cluster-defining height threshold of p<0.005.