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. 2016 Jul 14;16:477. doi: 10.1186/s12885-016-2461-4

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Examples of gene-rearrangement detection in filtration enriched-CTCs from NSCLC and mPCa patients by combined fluorescent staining and fluorescent in situ hybridization (FISH). a Example of ALK-rearrangement detection in NSCLC patients with an ALK-rearranged tumor. b Example of ROS1-rearrangement detection in NSCLC patients with a ROS1-rearranged tumor. c Example of RET-rearrangement detection in NSCLC patients with a RET-rearranged tumor. d Example of ERG-rearrangement detection in mPCa patients with an ERG-rearranged tumor. Gene rearrangements are shown by green and red. Scale: white bars = 10 μm