Table 1.
Clinicopathological features of gastric cancer in young and middle-aged patients
| Characteristics | Young | Middle-aged | P value |
|---|---|---|---|
| (n = 198) | (n = 1096) | ||
| Gender | <0.001 | ||
| male | 115 (58.1) | 895 (81.7) | |
| female | 83 (41.9) | 201 (18.3) | |
| Comorbidity | <0.001 | ||
| Negative | 189 (95.5) | 829 (75.6) | |
| Positive | 9 (4.5) | 267 (24.4) | |
| Hypertension | 0 (0.0) | 153 (14.0) | <0.001 |
| Coronary heart disease | 0 (0.0) | 22 (2.0) | 0.064 |
| Diabetes mellitus | 2 (1.0) | 53 (4.8) | 0.014 |
| COPDa | 0 (0.0) | 7 (0.6) | 0.389 |
| Brain infarction | 0 (0.0) | 18 (1.6) | 0.094 |
| Chronic hepatitis B | 6 (3.0) | 12 (1.1) | 0.044 |
| Tumor location | <0.001 | ||
| Upper | 15 (7.6) | 396 (36.1) | |
| Middle | 58 (29.3) | 242 (22.1) | |
| Lower | 123 (62.1) | 444 (40.5) | |
| whole | 2 (1.0) | 14 (1.3) | |
| Tumor size | 0.012 | ||
| < 5 cm | 117 (59.1) | 541 (49.4) | |
| ≥ 5 cm | 81 (40.9) | 555 (50.6) | |
| Histologic type | <0.001 | ||
| Well differentiated | 7 (3.5) | 123 (11.2) | |
| Moderately differentiated | 17 (8.6) | 323 (29.5) | |
| Poorly differentiated | 164 (82.8) | 587 (53.6) | |
| Signet ring cell or mucinous | 10 (5.1) | 63 (5.7) | |
| T status | 0.012 | ||
| T1 | 51 (25.8) | 192 (17.5) | |
| T2 | 31 (15.7) | 168 (15.3) | |
| T3 | 72 (36.4) | 390 (35.6) | |
| T4 | 44 (22.2) | 346( 31.6) | |
| N status | 0.067 | ||
| N0 | 62 (31.3) | 392 (35.8) | |
| N1 | 27 (13.6) | 205 (18.7) | |
| N2 | 41 (20.7) | 206 (18.8) | |
| N3 | 68 (34.3) | 293 (26.7) | |
| Tumor marker | |||
| CEA | <0.001 | ||
| Positive | 16 (8.1) | 245(22.4) | |
| Negative | 182 (91.9) | 851 (77.6) | |
| AFP | 0.007 | ||
| Positive | 3 (1.5) | 69 (6.3) | |
| Negative | 195 (98.5) | 1027 (93.7) | |
| CA19-9 | 0.020 | ||
| Positive | 26 (13.1) | 221 (20.2) | |
| Negative | 172 (86.9) | 875 (79.8) | |
| CA125 | 0.152 | ||
| Positive | 14 (7.1) | 51 (4.7) | |
| Negative | 184 (92.9) | 1045 (95.3) |
a COPD: chronic obstructive pulmonary disease