Table 2.
Survival analysis of the 1294 gastric cancer patients
| Parameter | Univariate Analysis | Mutivariate Analysis | ||||
|---|---|---|---|---|---|---|
| β | HR (95 % CI) | P value | β | HR (95 % CI) | P value | |
| Age (young/older group) | 0.152 | 0.859 (0.642–1.150) | 0.307 | −0.001 | 0.999 (0.727–1.372) | 0.993 |
| Gender (male/ female) | 0.234 | 1.264 (0.996–1.605) | 0.054 | 0.163 | 1.177 (0.916–1.513) | 0.202 |
| Comorbidity (negative/ positive) | 0.078 | 1.082 (0.824–1.420) | 0.572 | −0.027 | 0.973 (0.735–1.288) | 0.848 |
| Tumor location (upper/middle/lower third /whole) | −0.139 | 0.870 (0.774–0.977) | 0.019 | −0.042 | 0.958 (0.848–1.083) | 0.496 |
| Tumor size (<5 cm/≥5 cm) | 1.066 | 2.905 (2.320–3.637) | 0.000 | 0.238 | 1.268 (1.014–1.587) | 0.038 |
| Depth of invasion (T1/T2/T3/T4) | 0.824 | 2.280 (2.000–2.599) | 0.000 | 0.492 | 1.636 (1.408–1.901) | 0.000 |
| Lymph node metastasis (N0/N1/N2/N3) | 0.730 | 2.075 (1.880–2.290) | 0.000 | 0.505 | 1.657 (1.482–1.852) | 0.000 |
| Histologic type (well/moderately/poorly / signet ring cell or mucinous) | −0.194 | 0.824 (0.726–0.935) | 0.003 | −0.050 | 0.951 (0.840–1.078) | 0.436 |
| CEA (negative/ positive) | 0.841 | 2.318 (1.848–2.907) | 0.000 | 0.352 | 1.422 (1.110–1.822) | 0.005 |
| AFP (negative/ positive) | 0.640 | 1.896 (1.325–2.712) | 0.000 | 0.325 | 1.384 (0.952–2.011) | 0.088 |
| CA19-9 (negative/ positive) | 0.834 | 2.303 (1.839–2.882) | 0.000 | 0.365 | 1.441 (1.137–1.825) | 0.002 |
| CA125 (negative/ positive) | 1.176 | 3.242 (2.274–4.622) | 0.000 | 0.729 | 2.073 (1.442–2.979) | 0.000 |