Table 3.
Survival analysis of the 198 young gastric cancer patients
| Parameter | Univariate Analysis | Mutivariate Analysis | ||||
|---|---|---|---|---|---|---|
| β | HR (95 % CI) | P value | β | HR (95 % CI) | P value | |
| Gender (male/ female) | 0.557 | 1.746 (1.017–2.997) | 0.043 | 0.015 | 1.015 (0.572–1.800) | 0.959 |
| Comorbidity (negative/ positive) | −3.082 | 0.046 (0.000–10.360) | 0.265 | −11.166 | 0.000 (0.000-NA) | 0.973 |
| Tumor location (upper/middle/lower third /whole) | −0.487 | 0.615 (0.427–0.886) | 0.009 | −0.407 | 0.665 (0.428–1.035) | 0.048 |
| Tumor size (<5 cm/≥5 cm) | 1.063 | 2.894 (1.651–5.076) | 0.000 | 0.342 | 1.407(0.737–2.688) | 0.301 |
| Depth of invasion (T1/T2/T3/T4) | 1.001 | 2.722 (1.915–3.868) | 0.000 | 0.461 | 1.586 (1.067–2.358) | 0.023 |
| Lymph node metastasis (N0/N1/N2/N3) | 1.226 | 3.406 (2.349–4.939) | 0.000 | 1.066 | 2.905 (1.932–4.366) | 0.000 |
| Histologic type (well/moderately/poorly / signet ring cell or mucinous) | −0.216 | 0.806 (0.534–1.217) | 0.304 | −0.052 | 0.949 (0.638–1.413) | 0.797 |
| CEA (negative/ positive) | 0.640 | 1.896 (0.856–4.200) | 0.115 | 0.428 | 1.534 (0.608–3.871) | 0.365 |
| AFP (negative/ positive) | −3.026 | 0.049 (0.000–913.653) | 0.547 | −11.184 | 0.000 (0.000-NA) | 0.986 |
| CA19-9 (negative/ positive) | 1.036 | 2.817 (1.505–5.272) | 0.001 | 0.382 | 1.466 (0.710–3.026) | 0.301 |
| CA125 (negative/ positive) | 1.260 | 3.527 (1.578–7.886) | 0.002 | 1.087 | 2.965 (1.221–7.203) | 0.016 |