Table 4.

Peak level coordinates in the significant^* cluster during anticipation of reward and loss in 22q11DS COMT Val and Met hemizygotes

Reward-neutral
Group	Brain structure		BA	MNI coordinates			T score
				x	y	z
Val > Met	L	Cingulate gyrus	31	−6	−48	34	2.77
	L	Cingulate gyrus	31	−4	−40	44	2.57
	R	Cingulate gyrus	23	4	−28	28	2.86
	R	Middle frontal gyrus	6	16	−8	62	2.63
	R	Paracentral lobule	4	6	−38	62	3.48
	R	Paracentral lobule	5	8	−42	58	2.99
	L	Postcentral gyrus	3	−20	−32	56	2.93
	R	Postcentral gyrus	3	10	−36	66	3.67
	R	Postcentral gyrus	3	24	−34	58	3.09
	R	Posterior cingulate	30	6	−46	20	2.59
	R	Precentral gyrus	4	32	−32	56	3.24
	R	Precentral gyrus	4	34	−30	68	3.05
	R	Precentral gyrus	4	26	−30	64	3.01
	R	Precentral gyrus	6	22	−24	68	2.73
	L	Precuneus	31	−10	−48	36	2.69
	R	Precuneus	7	12	−66	40	3.00
Met > Val	No significant results
Loss-neutral
Group	Brain structure		BA	MNI coordinates			T score
				x	y	z
Val > Met	No significant results			−
Met > Val	L	Anterior cingulate	24	−2	30	20	2.91
	L	Caudate body	NA	−12	−2	20	3.42
	R	Caudate body	NA	10	−2	20	2.84
	L	Cingulate gyrus	23	−6	−34	28	3.58
	L	Cingulate gyrus	31	−16	−40	28	2.88
	L	Insula	13	−34	−6	16	2.86
	L	Posterior cingulate	23	−2	−40	22	3.29
	L	Putamen	NA	−24	−12	16	2.89
	L	Superior temporal gyrus	22	−64	−42	8	2.79
	L	Thalamus	NA	−18	−8	14	2.73

*p < 0.05 FWE-corrected at cluster level

L left, R right, BA Brodmann area