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. 2016 Mar 2;1(2):177–187. doi: 10.1016/j.parepi.2016.02.004

Fig. 2.

Fig. 2

Projected impact of annual and biannual targeted preventive chemotherapy with and without ivermectin co-administration on the mean worm burden of T. trichiura. The solid and dotted line pertain to standalone albendazole, and albendazole–ivermectin co-administration respectively. Two different transmission settings were explored; lower (R0 = 1.25), and higher (R0 = 1.75 — fitted). Results assume 75% treatment coverage of Pre-SAC and SAC. The drug efficacy was assumed to be 50% for standalone albendazole (Vercruysse et al., 2011a), and 95% when co-administering ivermectin (Speich et al., 2015). Note that those under five years of age cannot receive ivermectin and would only be treated with albendazole. ALB; Albendazole, IVM; Ivermectin.