Projected impact of annual and biannual targeted preventive chemotherapy with and without ivermectin co-administration on the mean worm burden of T. trichiura. The solid and dotted line pertain to standalone albendazole, and albendazole–ivermectin co-administration respectively. Two different transmission settings were explored; lower (R0 = 1.25), and higher (R0 = 1.75 — fitted). Results assume 75% treatment coverage of Pre-SAC and SAC. The drug efficacy was assumed to be 50% for standalone albendazole (Vercruysse et al., 2011a), and 95% when co-administering ivermectin (Speich et al., 2015). Note that those under five years of age cannot receive ivermectin and would only be treated with albendazole. ALB; Albendazole, IVM; Ivermectin.