Fig. 1.

The intake of the I. obliquus extract promoted body weight loss in middle-aged mice. Middle-aged and mature adult mice received water without (control) or with the I. obliquus extract for the indicated times and were analyzed for body weight. (A) Body weight of middle-aged mice (weight at day 0: 37.3 ± 3.5 g and 37.9 ± 5.1 g for the water and I. obliquus group, respectively; n = 4–5). (B) Amount of water drunk by middle-aged mice. (C) Body weight of mature adult mice (weight at day 0: 22.7 ± 1.8 g and 23.3 ± 2.1 g for the water and I. obliquus group, respectively; n = 8–9). (D) Amount of water drunk by mature adult mice. The data were normalized to the body weight at day 0 and expressed as the mean ± SD; *P < 0.05.