Fig. 4.

I. obliquus extract suppressed metastasis in mice injected with Lewis lung carcinoma cells. Mice drinking water with or without the I. obliquus aqueous extract received intravenous injection of 3LL cells. (A) Representative stereomicroscopic images of fixed mouse lungs containing carcinoma nodules. Arrowheads mark 3LL nodules on the lung. (B) The number of metastatic nodules counted under a stereomicroscope. Each dot represents a single mouse and lines show mean values (n = 4–6 per group). (C) Representative CT images of mouse lungs containing carcinoma nodules. Arrowheads mark 3LL nodules visible as dents on the lung. (D) The number of nodules measured in CT images of the lungs extracted at day 9 after cancer cell injection. Each dot represents a single mouse and lines show mean values (n = 4–5 per group; *P < 0.05).