Table 3.
Effect of Ca-deficient diet on creatinine and BUN levels in CCl4-induced toxicity.
| Creatinine (mg/dL) | BUN (mg/dL) | |
|---|---|---|
| Control | 0.34 ± 0.05 | 20.03 ± 2.82 |
| Normal diet + CCl4 | 0.72 ± 0.15** | 32.69 ± 10.82** |
| Ca-deficient diet + CCl4 | 0.71 ± 0.14** | 29.79 ± 7.59* |
Mice were fed a normal diet or a Ca-deficient diet from 4 weeks of age for a period of 4 weeks. At 8 weeks of age, mice were injected intraperitoneally with 2 g/kg CCl4. Plasma creatinine and blood urea nitrogen (BUN) were determined 24 h after injection. Data indicate mean ± S.D. for 6–9 mice.
P < 0.05.
P < 0.01 versus control.