Table 3.
Treatment characteristics, treatment response, and patterns of failure according to TLG
| Variable | Low TLG | High TLG | p-value |
|---|---|---|---|
| EQD2 (α/β ratio=10) | |||
| < 70 Gy | 18 (28.1) | 12 (36.4) | 0.41 |
| ≥ 70 Gy | 46 (71.9) | 21 (63.6) | |
| Treatment modality | |||
| 3D-CRT | 13 (20.3) | 10 (30.3) | 0.27 |
| IMRT | 51 (79.1) | 23 (69.7) | |
| Chemotherapy | |||
| None | 5 (7.8) | 0 | 0.29 |
| Concurrent | 32 (50.0) | 19 (57.6) | |
| Induction+concurrent | 27 (42.2) | 14 (42.4) | |
| RT response | |||
| CR | 56 (87.5) | 19 (57.6) | 0.001 |
| Non-CR | 8 (12.5) | 14 (42.4) | |
| Patterns of failure | |||
| Loco-regional failure | 4 (6.3) | 7(21.2) | 0.04 |
| Distant failure | 9(14.1) | 10 (30.3) | 0.06 |
Values are presented as number (%). TLG, total lesion glycolysis for whole tumor; EQD2, equivalent dose in 2 Gy fractions; 3D-CRT, 3-dimensional conformal radiation therapy; IMRT, intensity-modulated radiation therapy; RT, radiotherapy; CR, complete response.