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. 2016 Mar 16;115(6):3174–3185. doi: 10.1152/jn.00036.2015

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Fig. 6. — Effect of the M₃ muscarinic ACh receptor antagonist 4-DAMP and the nicotinic ACh receptor antagonist mecamylamine on ACh-induced K_Na channel activity in isolated Kenyon cells. A, top: representative traces of K_Na channel current in the control (left) and 10 μM ACh + 1 μM 4-DAMP (right) groups. Bottom: corresponding all-point amplitude histograms. C and O, closed and complete opening levels, respectively. B: NP_o before drug application (Control) and in the presence of 10 μM ACh + 1 μM 4-DAMP (ACh + 4-DAMP). Matching symbols connected with a line show the sequential experiment in the same cell. C, top: representative traces of K_Na channel current in the control (left) and 10 μM ACh + 20 μM mecamylamine (right) groups. Bottom: corresponding all-point amplitude histograms. D: NP_o before drug application (Control) and in the presence of 10 μM ACh + 20 μM mecamylamine (ACh + Mecamylamine). B and D: paired t-test; *P < 0.05.