The mean within manufacturer interlaboratory CV is on the X-axis; the mean manufacturer absolute bias is on the Y-axis. The black star represents the overall mean of all Laboratories. The dots (laboratory instruments) and squares (POCT instruments) represent specific manufacturers with colors for analytical principles: Immunoassays (green), Ion Exchange HPLC (red), Affinity HPLC (yellow), Capillary Electrophoresis (blue) and Dry Chemistry (grey). Abbott Architect c System (A), Abbott Architect I System (B), Axis-Shield Afinion (C), Beckman AU systems (D), Beckman UniCel DxC Synchron (E), Bio-Rad D10 (F), Bio-Rad Variant II (G), Bio-Rad Variant II Turbo (H), Bio-Rad Variant Turbo 2.0 (I), Roche Cobas c311 (J), Roche Cobas c500 series (K), Roche Cobas Integra 400 (L), Roche Cobas Integra 800 (M), Sebia Capillarys 2 Flex Piercing (N), Siemens Advia Chemistry Systems (O), Siemens DCA 2000/2000+ (P), Siemens DCA Vantage (Q), Siemens Dimension ExL (R), Siemens Dimension RxL (S), Siemens Dimension Vista (T), Siemens Dimension Xpand (U), Tosoh G7 Auto HPLC (V), Tosoh G8 Auto HPLC (W), Trinity Biotech HPLC (X), Trinity Biotech Premier Hb9210 (Y), Ortho Clin Diag Vitros 5,1 FS, 4600, 5600 Chem System (Z). For more details see Supplemental Data Table 1,