Table 1.

Congenital heart disease lesions divided by likelihood of being detected by pulse oximetry

Primary targets	Secondary targets	Possibly screenable	Not screenable
Hypoplastic left heart syndrome	Interrupted aortic arch/aortic atresia	Aortic stenosis with PDA	Coarctation of the aorta without a PDA
Pulmonary atresia	Coarctation of the aorta with PDA	Pulmonary stenosis	Ebstein’s anomaly without right-to-left shunt
Total anomalous pulmonary venous connection	Ebstein’s anomaly	Complete atrioventricular canal	Aortic stenosis without PDA
Transposition of the great arteries	Double-outlet right ventricle		Other left-to-right shunting lesions
Tetralogy of Fallot	Single ventricle physiology
Tricuspid atresia
Truncus arteriosus communis

Notes: Primary and secondary targets are cardiac lesions that will have hypoxemia in the newborn period. Lesions are considered possibly screenable or not screenable because of lesser degree of hypoxemia.

Abbreviation: PDA, patent ductus arteriosus.