TABLE 1.

Vegfr-1, and Vegfr-2 mRNA levels in K562 cells 48 hr after co-transfection with pMUG1 (empty vector), pMUG1-Myc-PRH, pSIH (empty vector), or pSIH-uPA

Levels of mRNA were determined by quantitative reverse transcriptase-PCR using specific primers and compared to GAPDH mRNA. Values are shown as -fold change over control values obtained (means and S.E.) in a sample co-transfected with pMUG1 (empty vector) and pSIH (empty vector) (n = 3).

Expression vector(s)	vegfr-1		vegfr-2		uPA		PRH
	Mean -fold change	S.E.	Mean -fold change	S.E.	Mean -fold change	S.E.	Mean -fold change	S.E.
pmug1-empty +pSIH3-empty	1		1		1		1
pmug1-PRH +pSIH3-empty	0.759a	0.011	0.623b	0.07	0.710	0.21	728.09	299.74
pmug1-empty +pSIH3-uPA	1.499	0.122	1.569	0.19	549.227	524, 01	3.35	0.946
pmug1-PRH +pSIH3-uPA	2.331	1.13	1.414	0.62	183.469	69.21	181.95	30.34

^a p < 0.005 relative to control (pmug1-empty+pSIH-empty).

^b p < 0.005 relative to control (pmug1-empty+pSIH-empty).