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Intracellular calcium traces of Tas2r105 (non-taster variant) in HEK293T cells stable expressing Gα15 (continuous line) and Gα16gust44 (dashed line) recorded in FLIPR experiments upon stimulation with six exemplary compounds, indicating that low efficacy activators of Tas2r105 resulted in lower or even absent responses in Gα15-expressing cells. Calibration bar denotes 2000 relative light units (y) and 1 min (x).
