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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Pain. 2016 Apr;157(4):806–817. doi: 10.1097/j.pain.0000000000000439

Figure 6. AEW treatment for 5 days in the back model increases TLR4 expression in spinal cord astrocytes.

Figure 6

(A,B) Double immunostaining of TLR4 with GFAP in the spinal cord dorsal horn (C3–C4) of vehicle (A) and AEW (5 d)-treated mice. Note that AEW increases GFAP-IR and TLR4-IR. Also note there is much more GFAP/TLR4 co-localization in chronic itch. Scale bar, 50 μm. (C) High magnification images from the boxes in B. Scale bars, 20 μm.