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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1974 May;37(5):598–605. doi: 10.1136/jnnp.37.5.598

Concurrence of multiple sclerosis and glioma

S Currie 1,2,1, H Urich 1,2
PMCID: PMC494706  PMID: 4365433

Abstract

Three cases are reported of concurrence of malignant gliomas (astrocytomas and glioblastomas) with multiple sclerosis (MS). This situation may lead to considerable diagnostic difficulties, yet an accurate appraisal is of prognostic, if not therapeutic, value. There is suggestive but inconclusive evidence that the two conditions may be causally related, malignant astrocytic tumours arising from plaques of MS. The small number of reported cases makes statistical analysis impossible, but the scanty literature may not reflect the true incidence.

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Selected References

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  1. Aubert L., Arroyo H., Daumas B., Tripier M. F. Un cas d'association entre sclérose en plaques et glioblastome cérébral. Rev Neurol (Paris) 1968 Oct;119(4):374–376. [PubMed] [Google Scholar]
  2. BRIHAYE J., PERIER O., STENUIT J. Multiple sclerosis associated with a cerebral glioma. J Neuropathol Exp Neurol. 1963 Jan;22:128–137. doi: 10.1097/00005072-196301000-00009. [DOI] [PubMed] [Google Scholar]
  3. Barnard R. O., Jellinek E. H. Multiple sclerosis with amyotrophy complicated by oligodendroglioma. History of recurrent herpes zoster. J Neurol Sci. 1967 Nov-Dec;5(3):441–455. doi: 10.1016/0022-510x(67)90084-6. [DOI] [PubMed] [Google Scholar]
  4. Behrman S. Pathology of papilloedema. Brain. 1966 Mar;89(1):1–14. doi: 10.1093/brain/89.1.1. [DOI] [PubMed] [Google Scholar]
  5. Boyazis R. M., Martin L., Bouteille M., Guazzi G. C., Manacorda A. Images histochimiques et ultrastructurales dans un cas de sclérose en plaques associée à un spongioblastome. Riv Patol Nerv Ment. 1967 Jan-Feb;88(1):1–20. [PubMed] [Google Scholar]
  6. Castaigne P., Escourolle R., Laplane D., Augustin P. Comas transitoires avec hyperthermie au cours de la sclérose en plaques. Encephale. 1966 May-Jun;55(3):191–211. [PubMed] [Google Scholar]
  7. IBRAHIM M. Z., ADAMS C. W. The relationship between enzyme activity and neuroglia in plaques of multiple sclerosis. J Neurol Neurosurg Psychiatry. 1963 Apr;26:101–110. doi: 10.1136/jnnp.26.2.101. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Ibrahim M. Z., Adams C. W. The relation between enzyme activity and neuroglia in early plaques of multiple sclerosis. J Pathol Bacteriol. 1965 Jul;90(1):239–243. doi: 10.1002/path.1700900126. [DOI] [PubMed] [Google Scholar]
  9. MATTHEWS W. B. Epilepsy and disseminated sclerosis. Q J Med. 1962 Apr;31:141–155. [PubMed] [Google Scholar]
  10. MUNCH-PETERSEN C. J. A case of disseminated sclerosis and glioma of the brain in the same patient. Acta Psychiatr Neurol. 1949;24(3-4):599–605. doi: 10.1111/j.1600-0447.1949.tb07342.x. [DOI] [PubMed] [Google Scholar]
  11. Mathews T., Moossy J. Mixed glioma, multiple sclerosis, and Charcot-Marie-Tooth disease. Arch Neurol. 1972 Sep;27(3):263–268. doi: 10.1001/archneur.1972.00490150071010. [DOI] [PubMed] [Google Scholar]
  12. ZIMMERMAN H. M., NETSKY M. G. The pathology of multiple sclerosis. Res Publ Assoc Res Nerv Ment Dis. 1950;28:271–312. [PubMed] [Google Scholar]

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