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Sodium butyrate (NaB)-induced CEA expression in HT29/219 and SW742 cells and resistance to anticancer drug 5-FU.
| Cell line |
NaB
(mM) |
CEA expression level
(ng/mg protein) |
IC
50
of 5-FU (μM)
a
Mean± SD |
* P-value |
|---|---|---|---|---|
| HT29/219 | 0 0.1 |
20.2± 0.3 28.5± 3.3 |
8.67± 3.2 12.1± 3.4 |
0.04 |
| SW742 | 0 0.1 |
0.00 0.00 |
21.9± 8.4 19.3± 3.2 |
0.26 |
Results are presented as mean± SD of three independent experiments, each done in triplicate.
P-value from Fisher’s exact test.
