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5-azacytidine (5-AZA)-induced CEA expression in HT29/219 and SW742 cells and resistance to anticancer drug 5-FU .
| Cell line |
5-AZA
(μM) |
CEA expression level
(ng/mg protein) |
IC
50
of 5-FU (μM)
a
Mean± SD |
* P-value |
|---|---|---|---|---|
| HT29/219 | 0 1 |
20.2± 0.3 29.2± 4.2 |
8.67± 3.2 13.65± 4.2 |
0.01 |
| SW742 | 0 1 |
0.00 0.00 |
21.9± 8.4 20.5± 5.2 |
0.33 |
Results are presented as mean± SD of three independent experiments, each done in triplicate.
P-value from Fisher’s exact test.
