Table 5.
Linear mixed model of CD68+ macrophages spatial distribution within the synovial sublining: progressive decline in CD68+ macrophages with distance from the lining layer in OA and in RA
| Effect | Disease | Estimate | Standard error | p value |
|---|---|---|---|---|
| Intercept | 5.23 | 1.91 | 0.003 | |
| ROI distance | −0.75 | 0.20 | <0.0001 | |
| Disease | OA | 0 | ||
| Disease | RA | 12.6 | 2.6 | <0.0001 |
| Interaction: ROI and disease | OA | 0 | ||
| Interaction: ROI and disease | RA | −0.77 | 0.27 | 0.003 |
Estimates without standard error refer to the reference category
ROI region of interest, OA osteoarthritis, RA rheumatoid arthritis