Skip to main content
. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Curr Opin HIV AIDS. 2016 Jul;11(4):376–382. doi: 10.1097/COH.0000000000000283

Figure 1. Mechanism of action of alemtuzumab.

Figure 1

Alemtuzumab lyses not only lymphocytes but monocytes and other non-CD4 T cells presumably via complement fixation, antibody-dependent cell-mediated cytotoxicity (ADCC), and by induction of apoptosis. Adapted with permission from Journal of Virus Eradication 2016; 2: 12–18.