Figure 1. Summary of thermal shift assays.

a, The effects of toremifene and ibuprofen on the melting temperature of EBOV GP at different pHs. The raw fluorescence traces are shown in Extended Data Fig. 1. Protein melting temperature at pH 5.2 at which crystals were grown is taken as the reference point. b, The melting temperatures of EBOV GP at different concentrations of toremifene or ibuprofen, at pH 5.2. Data are mean±s.d. (n=3).