Figure 3. Structure comparisons.

a, Structure of the apo GP monomer compared with the GP of the KZ52 Fab complex. b-d, Details of the structural differences at the glycan cap (b), β1-β2 hairpin (c) and the CX₆CC motif (d). The apo GP is coloured as in Fig. 1a, the GP in complex with Fab grey. e, Comparison of apo GP with GP from the GP-receptor complex shown in same style as a. f-g, close up views of the major structural differences at α1’ and α1 helices (f), and β1-β2 hairpin (g).