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. 2016 May 11;5:e14078. doi: 10.7554/eLife.14078

Figure 6. Order of the encapsulated cargo.

The spherically averaged density of cargo molecules inside a shell is shown as a function of radius for (A) εCC=1.6 and (B) εCC=1.3 for indicated values of the cargo-shell adhesion strength εSC, measured in equilibrium simulations. The density of the encapsulated cargo ranges from below random close packing to near hexagonal close packing density as εCC and εSC are increased (see Figure 3—figure supplement 3). A snapshot of cargo inside the shell is shown in Figure 5—figure supplement 2. The raw data for this figure is provided in Figure 6—source data 1.

DOI: http://dx.doi.org/10.7554/eLife.14078.022

Figure 6—source data 1. Raw data for Figure 6.
DOI: 10.7554/eLife.14078.023

Figure 6.

Figure 6—figure supplement 1. Ordering of the encapsulated cargo is primarily driven by confinement, not adhesion to the inner surface of the shell. .

Figure 6—figure supplement 1.

The spherically averaged density distribution is shown as a function of distance from the shell center, for simulations in which a preset number n of cargo molecules are trapped within a complete shell, with the cargo-shell attraction turned off (εSC=0). The value of n corresponding to each curve is given in the legend, and the value of the subunit-shell energy εSC is shown above each plot. These simulations were each run for 5×105 timesteps. The simulations shown in Figure 6 were also run with a complete shell; however, one excluder was rendered permeable to cargo molecules allowing the number of encapsulated cargo molecules to equilibrate. Those simulations were also each run for 5×105 timesteps. Raw data for this figure is provided in Figure 6—figure supplement 1—source data 1.
Figure 6—figure supplement 1—source data 1. Raw data for Figure 6—figure supplement 1.
DOI: 10.7554/eLife.14078.025