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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Drug Alcohol Depend. 2016 Jun 3;165:87–93. doi: 10.1016/j.drugalcdep.2016.05.016

Fig. 1.

Fig. 1

Effects of cannabidiol (left) and 8-OH-DPAT (right) following s.c. administration alone and in combination with Δ9-THC in rhesus monkeys discriminating Δ9-THC (0.1 mg/kg i.v.). Abscissae: vehicle (VEH) or dose of Δ9-THC in milligram per kilogram of body weight. Ordinates: mean (± S.E.M.) percentage of responding on the Δ9-THC lever (top) and mean (± S.E.M.) response rate expressed as a percentage of the VEH control rate (bottom). The dashed line is the dose-response function for Δ9-THC alone. Mean data for cannabidiol are n=6, except for discrimination data at 10 and 17.8 mg/kg cannabidiol, which are 5 out of the 6 monkeys tested. Mean data for 8-OH-DPAT are n=4, except for discrimination data at 0.178 mg/kg 8-OH-DPAT, which are 2 out of the 4 monkeys tested.