Skip to main content
. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Cell Signal. 2016 Jun 11;28(9):1364–1379. doi: 10.1016/j.cellsig.2016.06.012

Figure 9. PKG blockade by DT2 reverses the inhibitory effect of BAY60 on naïve ASM cell migration.

Figure 9

(A) Photomicrographs show VEH, BAY60, and BAY60+DT2 at times 0 and 16hr post-wounding scrape injury (scale bar=250 µm). (B) Quantification of ASM cell migration with BAY60 (10 µM) showing significantly reduced migration compared to VEH controls which was significantly reversed with concomitant PKG blockade by DT2 (1 µM). DT2 alone did not significantly alter cell migration compared to VEH controls (data not shown). Auto-contrast and red channel selection (Adobe Photoshop CS4 Extended) were applied uniformly to all photomicrographs. n = 2 independent experiments in duplicate. * p < 0.05 vs. VEH; $ p < 0.05 vs. BAY60.