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. Author manuscript; available in PMC: 2017 Jul 15.
Published in final edited form as: Clin Cancer Res. 2016 Feb 5;22(14):3630–3642. doi: 10.1158/1078-0432.CCR-15-1434

Figure 4. Evidence of immune activation in “mesenchymal” compared to “epithelial” adenocarcinoma.

Figure 4

Gene expression levels of multiple immune stimulatory molecules including CD80, CD86, OX40L, 4-1BB, ICOS, CD127 were analyzed in “mesenchymal” lung adenocarcinoma versus “epithelial” lung adenocarcinoma in tumor tissues from (A) TCGA, (B) PROSPECT. Gene expression of IFN-γ and IFN-γ inducible genes including CXCL10 and IDO were also analyzed in “mesenchymal” in comparison to “epithelial” lung adenocarcinoma in tumor tissues from (C) TCGA, (D) PROSPECT.